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12.18.12 - As pluripotent stem cells differentiate in vitro into a mixture of different lineages, purification of the differentitated cells, as well as separation from their tumor-forming progenitors, is essential for applications to regenerative medicine. Unfortunately, conventional separation techniques require labeling or genetic modification, neither of which is ideal for such clinical applications.

Biopico is developing an 'On-the-Fly Field-potential Sensing Electrod Track' (OFFSET) microdevice for label-free cell sorting of induced pluripotent stem cells and their differentiated progeny based on response to electrical stimulation.